EFFECT OF ANTIOXIDANTS ON SPERM DNA FRAGMENTATION

The effect of rhFSH on Sperm DNA Fragmentation and sperm parameters in Oligozoospermia Infertile Men

Background: One of the main causes of male infertility is the negative effects of oxidative stress. Follicle-stimulating hormone (FSH) plays an essential role in spermatogenesis, as well as in the maintenance of sperm DNA integrity. This study aimed to determine whether the recombinant human follicle-stimulating hormone (rhFSH) treatment of sperm parameters could positively affect sperm DNA and...

Antioxidants for elevated sperm DNA fragmentation: a mini review

P-240: Effect of Oxidative Stress on DNA Fragmentation Index in Sperm of Mature Mice

Background: One of the major factors affecting on male infertility is oxidative stress (OS). Two main sources of ROS production are leukocytes and spermatozoa. The ROS such as tertiary-butyl hydroperoxide (TBHP) may damage and fragmentate to sperm DNA, which can lead to complications in the offspring. In this study, we will investigate the effect of od on DNA fragmentation index (DFI) in sperm ...

P-33: The Effect of the Pentoxifylline on Human Sperm DNA Fragmentation

Background: It is stated that pentoxifyline can improve sperm motility and suggested to use in ART for asthenozoospermia. But, probable effect of this drug on sperm DNA in unknown. Our main goal was to evaluate the impact of pentoxifyline on sperm DNA fragmentation. Materials and Methods: Thirty eight asthenozoospermic patients were selected for this prospective study. After direct swim-up, spe...

Sperm DNA fragmentation

tau.amegroups.com © Translational Andrology and Urology. All rights reserved. It is an honour to write the foreword to this focused issue of TAU on sperm DNA fragmentation (SDF). From my time as a first generation embryologist in the early days at the University of Cambridge with Professor Robert Edwards and in my current role at the London Women’s Clinic, I have become acutely aware of the num...